Table 1 Patient groups analyzed by quantitative RT-PCR and immunohistochemistry
From: Role of tight junction proteins in gastroesophageal reflux disease
Quantitative RT-PCR | Controls (n = 26) | NERD (n = 37) | ERD (n = 47) |
|---|---|---|---|
Sex (male/female) | 6/20 | 6/31 | 31/16# |
Age (mean, sd, range) | 52.3 ± 17.6 | 47.0 ± 14.1 | 47.5 ± 15.4 |
(20–79) | (18–72) | (20–79) | |
H. pylori-status (positive) | 5/21 | 7/30 | 12/35 |
(23.1 %) | (22 %) | (29.2 %) | |
Immunohistochemistry | Controls (n = 12) | NERD (n = 13) | ERD (n = 16) |
Sex (male/female) | 2/10 | 4/9 | 10/6# |
Age (mean, sd, range) | 46.2 ± 19.1 | 48.9 ± 9.5 | 48.6 ± 14.1 |
(20–75) | (35–64) | (29–72) | |
H. pylori-status (positive) | 4/8 | 2/11 | 7/9 |
(33.3 %) | (15.4 %) | (43.8 %) |