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Table 1 Patient groups analyzed by quantitative RT-PCR and immunohistochemistry

From: Role of tight junction proteins in gastroesophageal reflux disease

Quantitative RT-PCR Controls
(n = 26)
NERD
(n = 37)
ERD
(n = 47)
Sex (male/female) 6/20 6/31 31/16#
Age (mean, sd, range) 52.3 ± 17.6 47.0 ± 14.1 47.5 ± 15.4
(20–79) (18–72) (20–79)
H. pylori-status (positive) 5/21 7/30 12/35
(23.1 %) (22 %) (29.2 %)
Immunohistochemistry Controls (n = 12) NERD (n = 13) ERD (n = 16)
Sex (male/female) 2/10 4/9 10/6#
Age (mean, sd, range) 46.2 ± 19.1 48.9 ± 9.5 48.6 ± 14.1
(20–75) (35–64) (29–72)
H. pylori-status (positive) 4/8 2/11 7/9
(33.3 %) (15.4 %) (43.8 %)