Variable

Non FP

FP

OR(95% CI)

Pvalue


n = 77

n = 32


Age, year

50.8(1.4)

53.4(2.0)
 
.316

Gender, male/female (n)

35/42

16/16
 
.679

BMI, kg/m^{2}

24.34(0.37)

25.37(0.68)
 
.155

HCV genotype, 1/non1 (n)

38/39

15/17
 
.836

HCV RNA, x 10^{6}, copies/mL

7.14(1.12)

10.61(3.12)
 
.194

ALT, IU/L

83.01(9.40)

133.88(15.02)
 
.004

ALT/ULN (n)
    
<1x

24

2

reference
 
≧1x <2x 
25

10

4.8(0.924.2)

.057

≧2x <3x 
16

5

3.8(0.621.7)

.140

≧3x 
12

15

15.0(2.976.6)

.001*

ActiTest A score (n)
   
.

0.000.35

31

2

reference
 
0.360.75

24

13

8.4(1.740.8)

.008*

0.761.00

22

17

11.9(2.557.2)

.002*

Bilirubin, umol/L

15.76(0.56)

19.30(1.12)
 
.002

Cr, umol/L

70.82(2.82)

74.14(4.55)
 
.817

INR

1.00(0.01)

1.05(0.02)
 
.007

Na, meq/L

137.94(0.28)

137.81(0.46)
 
.527

Platelet, x 10^{9}/L

184.21(6.20)

158.31(9.37)
 
.025

METAVIR F1/2/3 (n)

38/32/7

8/8/16
 
<.001

METAVIR A (n)
    
A0

28

3

reference
 
A1

45

15

3.1(0.811.7)

.094

A23

4

14

32.7(6.4166.5)

<.001*

Hepatic steatosis S0/1/2/3/4(n)

10/28/35/3/1

5/9/17/1/0
 
.903

Liver SWV, m/s

1.34(0.03)

2.40(0.11)
 
<.001

FibroTest, F score

0.51(0.03)

0.72(0.04)
 
<.001

 Thirtytwo patients of the 109 patients with METAVIR F1, F2 and F3 were false positive (32/109, 29%) in liver fibrosis evaluation using acoustic radiation force impulse elastography. False positive case numbers were: 8 (8/46, 17%) (ARFI LSM > 1.55 m/s) in METAVIR F1; 8 (8/40, 25%) (LSM > 1.81 m/s) in F2; 16 (16/23, 70%) (LSM > 1.98 m/s) in F3 stages. Continuous variables were presented as mean (standard error) and examined using the Student’s ttest. Categorical variables were estimated using Fisher's exact test or univariate binary logistic regression*. ALT, serum alanine aminotransferase; ARFI, acoustic radiation force impulse; CI, confidence interval; Cr, serum creatinine; FP, false positivity; INR, international normalized ratio of prothrombin time; LSM, liver stiffness measurement; METAVIR A, activity; METAVIR F, fibrosis; Na, serum sodium; non FP, true positive + true negative + false negative; OR, odds ratio; SWV, shear wave velocity.