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Table 4 ICERs for other Patient-Directed Interventions to Improve Colorectal Cancer Screening

From: Cost-effectiveness of a mailed educational reminder to increase colorectal cancer screening

Study Patients Target Population Target CRC screening test Cost of Intervention Intervention Baseline Screening Rate Change in Effectiveness ICER
Lee et al. 2009 775 Veterans aged ≥ 50 years who were average risk for CRC FOBT Mailed Reminder $2.49 48.4% 16.2% $15
Lewis et al. 2008 237 Patients in a University-based practice age ≥50 years who were average risk for CRC FOBT, FS, colonoscopy Mailed package that included a letter from their PCP, a CRC screening decision aid, and instructions for obtaining each screening test without an office visit $11 4% 11% $94
Lairson et al. 2007 1546 Patients in a University-based practice ages 50-74 years who were average risk for CRC FOBT, FS, colonoscopy barium enema Patients randomized into 4 groups: control, standard group (SI) consisting of mailed informational brochure, invitation letter, FOBT cards, and reminder letter; tailored intervention (TI) consisting of standard intervention plus motivational messages based on patient-specific survey data; tailored interventions (TIP) consisting of tailored intervention plus reminder phone call $42 for SI $150 for TI $200 for TIP 33% 13% for SI TI and TIP did not yield much significant change in effective ness $319 for SI $5842 for TIP
Shankaran et al. 2006 781 Patients in a University-based practice ages ≥50 years who received referrals for screening colonoscopy Colonoscopy Mailed informational Brochure/Reminder $5 59% 12% $43
Sequist et al. 2010 21,860 Patients aged 50-80 years across 11 health centers who were average risk for CRC FOBT, FS, colonoscopy Patient mailing with FOBT kit, telephone line to schedule colonoscopy, and mailed reminder 6 months later $5.48 38% 6% $94
  1. FOBT: Fecal occult blood test, CRC: Colorectal cancer, FS: Flexible sigmoidoscopy