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Table 4 ICERs for other Patient-Directed Interventions to Improve Colorectal Cancer Screening

From: Cost-effectiveness of a mailed educational reminder to increase colorectal cancer screening

Study

Patients

Target Population

Target CRC screening test

Cost of Intervention

Intervention

Baseline Screening Rate

Change in Effectiveness

ICER

Lee et al. 2009

775

Veterans aged ≥ 50 years who were average risk for CRC

FOBT

Mailed Reminder

$2.49

48.4%

16.2%

$15

Lewis et al. 2008

237

Patients in a University-based practice age ≥50 years who were average risk for CRC

FOBT, FS, colonoscopy

Mailed package that included a letter from their PCP, a CRC screening decision aid, and instructions for obtaining each screening test without an office visit

$11

4%

11%

$94

Lairson et al. 2007

1546

Patients in a University-based practice ages 50-74 years who were average risk for CRC

FOBT, FS, colonoscopy barium enema

Patients randomized into 4 groups: control, standard group (SI) consisting of mailed informational brochure, invitation letter, FOBT cards, and reminder letter; tailored intervention (TI) consisting of standard intervention plus motivational messages based on patient-specific survey data; tailored interventions (TIP) consisting of tailored intervention plus reminder phone call

$42 for SI $150 for TI $200 for TIP

33%

13% for SI TI and TIP did not yield much significant change in effective ness

$319 for SI $5842 for TIP

Shankaran et al. 2006

781

Patients in a University-based practice ages ≥50 years who received referrals for screening colonoscopy

Colonoscopy

Mailed informational Brochure/Reminder

$5

59%

12%

$43

Sequist et al. 2010

21,860

Patients aged 50-80 years across 11 health centers who were average risk for CRC

FOBT, FS, colonoscopy

Patient mailing with FOBT kit, telephone line to schedule colonoscopy, and mailed reminder 6 months later

$5.48

38%

6%

$94

  1. FOBT: Fecal occult blood test, CRC: Colorectal cancer, FS: Flexible sigmoidoscopy