Figure 3From: Early stage transplantation of bone marrow cells markedly ameliorates copper metabolism and restores liver function in a mouse model of Wilson disease Effect of BM cells transplantation on the ceruloplasmin oxidase activity. The serum ceruloplasmin oxidase activity was measured using an o-dianisidine dihydrochloride test in tx mice at 1, 4, 8 and 12 weeks post-transplant. (A) Ceruloplasmin oxidase activity in mice treated with DL BM cells or saline or tx BM cells transplantation at 2 months of age. (B) Ceruloplasmin oxidase activity in mice treated with DL BM cells or saline or tx BM cells transplantation at 5 months of age (n = 10). Values were mean ± SD and analyzed using ANOVA. *P < 0.05, compared with the saline-treated group; ▲P < 0.05, compared with the tx BM cells treated group.Back to article page