From: Most bowel cancer symptoms do not indicate colorectal cancer and polyps: a systematic review
Symptom | DOR* (95% CI*) | AUC** | Sensitivity (95% CI) | 1-specificity (95% CI) | LR+ (95% CI) | LR- (95% CI) |
---|---|---|---|---|---|---|
Rectal bleeding# | 2.6 (1.9-3.6) p < 0.001 | 0.66 | 0.46 (0.38-0.55) | 0.25 (0.19-0.31). | 1.9 (1.5-2.3) | 0.7 (0.6-0.8) |
Blood mixed with stool: | 3.1 (2.0-4.8) p < 0.001 | 0.68 | 0.49 (0.30-0.69) | 0.24 (0.13-0.40) | 2.1 (1.5-2.8) | 0.7 (0.5-0.9) |
Blood: dark red | 3.9 (1.7 - 9.2) P = 0.004 | 0.71 | 0.29 (0.09-0.65) | 0.10 (0.03-0.28) | 3.1 (1.6-6.0) | 0.8 (0.6-1.1) |
Change in bowel habit | 1.5 (0.8-2.8) p = 0.16 | 0.57 | 0.32 (0.21-0.46) | 0.24 (0.15-0.35) | 1.4 (0.9-2.1) | 0.9 (0.7-1.1) |
Constipation | 1.1 (0.8-1.5) p = 0.48 | 0.52 | 0.12 (0.08-0.18) | 0.11 (0.07-0.16). | 1.1 (0.8-1.5) | 1.0 (1.0-1.0) |
Diarrhoea | 0.9 (0.4-1.7) p = 0.65 | 0.47 | 0.15 (0.07-0.28) | 0.17 (0.09-0.29) | 0.9 (0.5-1.6) | 1.0 (0.9-1.1) |
Abdominal pain | 0.7 (0.5-1.1) p = 0.12 | 0.45 | 0.19 (0.13-0.28) | 0.24 (0.17-0.33). | 0.8 (0.6-1.1) | 1.1 (1.0-1.2) |
Weight loss | 2.9 (1.6-5.0) p = 0.001 | 0.67 | 0.20 (0.12-0.31) | 0.08 (0.05-0.13). | 2.5 (1.5-4.0) | 0.9 (0.8-1.0) |