Table 1 Overview of results: Symptoms association with cancer.
From: Most bowel cancer symptoms do not indicate colorectal cancer and polyps: a systematic review
| Symptom | DOR* (95% CI*) | AUC** | Sensitivity (95% CI) |
1-specificity (95% CI) | LR+ (95% CI) | LR- (95% CI) |
|---|---|---|---|---|---|---|
| Rectal bleeding# |
2.6 (1.9-3.6) p < 0.001 | 0.66 |
0.46 (0.38-0.55) |
0.25 (0.19-0.31). |
1.9 (1.5-2.3) |
0.7 (0.6-0.8) |
| Blood mixed with stool: |
3.1
(2.0-4.8) p < 0.001 | 0.68 |
0.49
(0.30-0.69) |
0.24
(0.13-0.40) |
2.1
(1.5-2.8) |
0.7
(0.5-0.9) |
| Blood: dark red |
3.9
(1.7 - 9.2) P = 0.004 | 0.71 |
0.29
(0.09-0.65) |
0.10
(0.03-0.28) |
3.1
(1.6-6.0) |
0.8
(0.6-1.1) |
| Change in bowel habit |
1.5 (0.8-2.8) p = 0.16 | 0.57 |
0.32 (0.21-0.46) |
0.24 (0.15-0.35) |
1.4 (0.9-2.1) |
0.9 (0.7-1.1) |
| Constipation |
1.1 (0.8-1.5) p = 0.48 | 0.52 |
0.12 (0.08-0.18) |
0.11 (0.07-0.16). |
1.1 (0.8-1.5) |
1.0 (1.0-1.0) |
| Diarrhoea |
0.9 (0.4-1.7) p = 0.65 | 0.47 |
0.15 (0.07-0.28) |
0.17 (0.09-0.29) |
0.9 (0.5-1.6) |
1.0 (0.9-1.1) |
| Abdominal pain |
0.7 (0.5-1.1) p = 0.12 | 0.45 |
0.19 (0.13-0.28) |
0.24 (0.17-0.33). |
0.8 (0.6-1.1) |
1.1 (1.0-1.2) |
| Weight loss |
2.9 (1.6-5.0) p = 0.001 | 0.67 |
0.20 (0.12-0.31) |
0.08 (0.05-0.13). |
2.5 (1.5-4.0) |
0.9 (0.8-1.0) |