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Table 2 The effects of H. pylori eradication therapy on 40 patients with diffuse duodenal nodular hyperplasia.

From: Diffuse duodenal nodular lymphoid hyperplasia: a large cohort of patients etiologically related to Helicobacter pyloriinfection

Disease severity All patients
(n = 40)
Eradicated group
(n = 26)
Not eradicated group
(n = 14)
  H. pylori
therapy
P value H. pylori
therapy
P value H. pylori
therapy
P value
  Before After   Before After   Before After  
Persistent symptoms 40 23 <0.001a 26 12 <0.001a 14 11 0.22a
Grade of nodular disease
Grade 0 0 5 0.005b 0 5 0.002b 0 0 0.91b
Grade 1 4 12   2 9   2 3  
Grade 2 10 11   7 7   3 3  
Grade 3 20 10   14 4   6 4  
Grade 4 6 2   3 1   3 4  
Mean ± 1SD Score 2.70 ± 0.84 1.83 ± 1.06 <0.001c 2.69 ± 0.79 1.50 ± 1.10 <0.001c 2.71 ± 0.96 2.64 ± 1.15 0.58c
  1. a = Fisher's exact test 2 × 2 table; b = Fisher's exact test rxc table; c = students t test.