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Figure 2 | BMC Gastroenterology

Figure 2

From: Differences in cerebral response to esophageal acid stimuli and psychological anticipation in GERD subtypes - An fMRI study

Figure 2

Characteristic brain activation in the four GERD subgroups and controls. 2A. Average intra-group cerebral activation during esophageal acid infusion: Control group: no ROI was activated. RE group: PFC, IC and ACC were activated. NERD+ group: PFC and IC were activated. NERD-SI+ group: PFC was activated. NERD-SI- group: PFC, IC and ACC were activated. 2B. Average inter-group cerebral activation during esophageal acid infusion. RE vs. NERD+: PFC and ACC were significantly activated in RE compared with the NERD group. RE vs. NERD-SI+: ACC and IC were significantly activated in RE compared with the NERD-SI+ group. RE vs. NERD-SI-: PFC and IC were significantly activated in RE compared with the NERD-SI- group. NERD-SI+ vs. NERD+: PFC were significantly activated in NERD-SI+ compared with the NERD+ group. NERD-SI+ vs. NERD-SI-: The PFC was significantly activated in NERD-SI+ compared with the NERD-SI- group.

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