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Table 9 Summary of short chain fatty acids (SCFA's) in stool.

From: Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

 

Acetate

Butyrate

Propionate

Valerate

Total SCFA's

Autism/Asperger's

3.5 +/- 1.4

1.63 +/- 1.2

1.28 +/- 0.5

0.22 +/- 0.1

6.7 +/- 2.8

A-Probiotics

(n = 19)

2.94 +/- 1.4

1.00 +/- 0.7

1.02 +/- 0.37

0.17 +/- 0.10

5.13 +/- 2.2

A-No-Probiotics

(n = 38)

3.84 +/- 1.3

1.95 +/- 1.25

1.43 +/- 0.54

0.24 +/- 0.12

7.5 +/- 2.8

Controls

5.2 +/- 1.6

2.00 +/- 0.9

1.64 +/- 0.6

0.36 +/- 0.3

9.2 +/- 2.6

Ttest Comparisons

     

A-Probiotics vs. A-No Probiotics

P = 0.02

P = 0.003

P = 0.004

P = 0.02

P = 0.002

A-Probiotics vs. Controls

P = 0.000002

P = 0.0001

P = 0.00007

P = 0.02

P = 0.0000002

A-No-Probiotics vs. Controls

P = 0.00009

n.s.

P = 0.09

P = 0.05

P = 0.006

All autism vs. Controls

P = 0.0000003

(-32%)

P = 0.005

(-18%)

P = 0.002

(-22%)

P = 0.005

(-39%)

P = 0.00002

(-27%)

  1. Each fatty acid is expressed in units of mg/mL.