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Table 3 Transcript levels of TLRs and pro-inflammatory cytokines in colonic mucosa from UC patients and Controls

From: Transcript levels of Toll-Like receptors 5, 8 and 9 correlate with inflammatory activity in Ulcerative Colitis

GENE mRNA Control N = 36 UC Patients N = 51 UC Quiescent N = 21 UC Active N = 31 Control vs UC Control vs UC Quiescent Control vs UC Active UC Quiescent vs Active
  Transcript Levels P value
TLR1 0.75±0.50 1.12±1.63 1.33±2.51 0.98±0.53 0.26 0.64 0.13 0.11
TLR2 0.63±0.25 1.63±2.5 0.72±0.4 2.55±3.30 0.14 0.9 0.001 0.002
TLR3 0.54±0.25 0.75±0.5 0.87±0.60 0.63±0.39 0.6 0.18 0.7 0.27
TLR4 0.64±0.23 1.3±0.94 1.01±0.62 1.55±1.12 0.002 0.015 0.0001 0.04
TLR5 0.94±0.58 0.86±0.5 0.71±0.46 0.96±0.52 0.75 0.14 0.55 0.06*
TLR6 0.91±0.61 0.8±0.67 0.59±0.36 0.94±0.79 0.52 0.11 0.56 0.19
TLR7 0.71±0.45 0.62±0.79 0.77±1.21 0.52±0.27 0.86 0.14 0.13 0.82
TLR8 1.13±0.73 1.96±2.19 0.88±0.59 2.67±2.56 0.04 0.22 0.001 0.0005
TLR9 0.75±0.57 1.12±1.1 0.66±0.37 1.60±1.26 0.037 0.95 0.004 0.006
TOLLIP 0.79±0.21 0.84±0.28 0.85±0.32 0.83±0.26 0.41 0.69 0.82 0.86
TNF 0.96±1.28 0.84±0.79 0.4±0.37 1.24±0.86 0.96 0.01 0.023 < 0.001
IL6 1.8±3.5 8±19.5 1.6±3.2 11±23 0.039 0.8 < 0.001 < 0.001
  1. Transcript levels are shown as means and standard deviations. P with significance are underlined and * for trend.