Clinical benefit of gluten-free diet in screen-detected older celiac disease patients

BMC Gastroenterology

Table 2 Symptoms and quality of life

	Screen-detected celiac patients
	At the diagnosis After gluten-free diet		p-value^a	Non-celiac controls	p-value ^b
GSRS ^c
Diarrhea	2.1 (1.7-2.6)	1.5 (1.2-1.9)	0.009	1.6 (1.5-1.8)	0.091
Indigestion	2.8 (2.4-3.2)	2.0 (1.6-2.3)	< 0.001	2.4 (2.0-2.7)	0.117
Constipation	2.1 (1.7-2.5)	1.8 (1.5-2.1)	0.343	2.0 (1.6-2.3)	0.813
Abdominal pain	2.1 (1.7-2.4)	1.7 (1.4-2.0)	0.020	1.8 (1.5-2.1)	0.203
Reflux	1.8 (1.4-2.2)	1.4 (1.2-1.7)	0.040	1.5 (1.8-1.2)	0.161
Total score	2.2 (1.9-2.5)	1.7 (1.5-2.0)	0.001	1.9 (1.7-2.1)	0.133
PGWB^d
Anxiety	23 (21-24)	24 (22-25)	0.256	25 (24-26)	0.063
Depression	16 (15-17)	16 (15-17)	0.429	16 (16-17)	0.713
Well-being	16 (15-17)	17 (16-18)	0.011	17 (16-17)	0.364
Self-control	15 (14-16)	15 (14-16)	0.942	15 (15-16)	0.593
General health	13 (12-14)	12 (11-14)	0.243	14 (14-15)	0.030
Vitality	17 (16-18)	18 (16-19)	0.100	19 (18-19)	0.110
Total score	100 (93-106)	102 (95-109)	0.620	106 (104-108)	0.355

Gastrointestinal symptom score (GSRS) and psychological general well-being (PGWB) in older celiac disease patients before and after dietary treatment, compared to non-celiac controls
^a Comparison between celiac patients at the diagnosis and after gluten-free diet
^b Comparison between celiac patients at the diagnosis and non-celiac controls
^c Gastrointestinal symptom rating scale; higher scores indicate more gastro-intestinal symptoms
^d Psychological general well-being; higher scores indicate better quality of life

ISSN: 1471-230X