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Table 1 Correlation between the protein expression of pGSK-3βTyr216 and clinicopathological factors for 281 human gastric caicinoma specimens.

From: Constitutive activation of glycogen synthase kinase-3β correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer

  Active GSK-3β
Positive (%)
Active GSK-3β
Negative (%)
Pvalue
Total (n = 281) 129 (46) 152 (54)  
Age (y)    
   0-39 21 (46) 25 (54) 0.881
   40-65 83 (47) 94 (53)  
   66-99 25 (43) 33 (57)  
Gender    
   Male 94 (49) 98 (51) 0.157
   Female 35 (39) 54 (61)  
Locus    
   Antrum 63 (42) 86 (58) 0.230
   Body and Cardia 66 (50) 66 (50)  
WHO classification    
   WD 21 (78) 6 (22) < 0.001*
   MD 42 (53) 37 (47)  
   PD 44 (37) 74 (63)  
Lauren's classification    
   Intestinal 63 (59) 44 (41) < 0.001*
   Diffuse 62 (37) 107 (63)  
   Mixed 4 (80) 1 (20)  
TNM stage    
   I 53 (69) 24 (31) < 0.001*
   II 60 (43) 80 (57)  
   III 16 (27) 44 (73)  
   IV 0 (0) 4 (100)  
Lymphatic invasion    
   Absent 104 (53) 93 (47) < 0.001*
   Present 25 (30) 59 (70)  
Lymph node metastasis    
   Absent 63 (63) 37 (37) < 0.001*
   Present 66 (36) 115 (64)  
Distant metastasis    
   Absent 124 (47) 141 (53) 0.304
   Present 5 (31) 11 (69)  
  1. WD: well-differentiated adenocarcinoma; MD: moderately-differentiated adenocarcinoma; PD: poorly-differentiated adenocarcinoma.
  2. * Considered to be statistically significant (< 0.05).