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Table 1 Characteristics of studies included in the meta-analysis

From: Association between HLA-DRB1 alleles polymorphism and hepatocellular carcinoma: a meta-analysis

Author

Year

Country/ Region

Number of HCC (M/F), age

Number of controls (M/F), age

Number of DRB1 alleles studied

HLA genotyping method

Donaldson[11]

2001

Hong Kong

84(79/5),55

124(-/-), NA

13

PCR-SSOP

De Re[12]

2004

Italy

29(-/-), NA

144(-/-), NA

13

PCR-SSP

Yuan[13]#

2004

China

10(-/-), NA

50(30/20),43.7 ± 12.9

3

PCR-SSP

López-Vázquez[14]

2004

Spain

46(27/19),62 ± 8

48(19/29),56 ± 12

11

PCR-SSOP

Yuan[15]#

2005

China

10(-/-), NA

50(30/20),43.7 ± 12.9

2

PCR-SSP

Kummee[16]

2007

Thai

50(38/12), 57.5 ± 14.2

100(68/32),50.8 ± 13.9

2

PCR-SSP

El-Chennawi[17]

2008

Egypt

50(45/5),51.16 ± 6.16

50(44/6),48.88 ± 9.22

11

PCR-SSP

Pan[18]

2009

China

62(52/10),53.58

50(29/21),30.12

8

PCR-SSP

  1. NA, not available; PCR-SSOP, PCR-sequence-specific oligonucleotides probes; PCR-SSP, PCR-sequence-specific primer;
  2. # These two studies described different allele polymorphisms with the same subjects.