Table 1 Details of patients at the time of PBC diagnosis, placement on the waiting list and transplantation.

Age (mean ± SD)

45.4 ± 7.2

45.4 ± 7.6

53.1 ± 7.6

53.0 ± 7.1

53.4 ± 7.6

53.8 ± 7.2

Female n (%)

56 (92)

36 (81)

56 (92)

36 (81)

56 (92)

36 (81)

UDCA n (%)

23 (38) started

36 (82) started

23 (38)

36 (82)

23 (38)

36 (82)

Bilirubin (ULN)

1.4(0.2-16.1)*)

1.0(0.4-6.6)*)

6.3(0.5-37.7)*)

3.6(0.5-29.6)*)

7.4 (0.4-37.7)

6.4 (0.5-43.1)

Albumin (LLN)

1.1 (0.7-2.6)

1.1 (0.8-2.0)

0.8 (0.5-6.5)

0.9 (0.6-1.2)

0.8 (0.5-6.5)

0.9 (0.3-1.3)

ALP (ULN)

5.0(1.1-19.4)*)

4.3(1.1-9.1)*)

4.5 (0.4-14.5)

2.8 (0.4-16.2)

4.1(0.4-12.6)#)

2.3(0.2-7.9)#)

AST (ULN)

2.4 (0.6-8.9)

2.1 (0.6-10.8)

3.3 (0.6-8.9)

2.8 (0.6-14.7)

2.9 (0.5-26.3)

3.0 (0.8-19.4)

ALT (ULN)

3.3 (0.7-9.3)

2.7 (0.9-14.3)

2.4 (0.4-9.3)

2.3 (0.6-12.8)

2.5 (0.2-14.6)

2.4 (0.4-18.2)

Creatinin (ULN)

0.6 (0.5-0.8)

0.7 (0.5-1.3)

0.7 (0.1-1.6)

0.7 (0.4-2.5)

0.7 (0.1-1.6)

0.7 (0.5-2.7)

INR

0.9(0.7-1.9)*)

0.8(0.6-1.0)*)

1.0 (0.7-2.4)

1.0 (0.7-1.7)

1.1 (0.7-2.8)

1.0 (0.7-2.2)

MELD (mean ± SD)

7.3 ± 2.7

7.0 ± 2.1

12.4 ± 5.1*)

14.5 ± 6.0*)

14.5 ± 6.0

13.0 ± 6.6

Prognostic class n (%)

Early

11 (18)

18 (41)

0 (0)

3 (7)

2 (3)

4 (9)

Moderately advanced

26 (43)

7 (16)

12(20)

11 (25)

8 (13)

11 (25)

Advanced

11 (18)

10 (23)

49 (80)

30 (68)

51 (84)

29 (66)

Insufficient data

13 (21)

9 (20)

0 (0)

0 (0)

0 (0)

0 (0)