The gene-reduction effect of chromosomal losses detected in gastric cancers

BMC Gastroenterology

Table 1 Relationships of the clinicopathologic characteristics and single chromosomal loss

Characteristics		3p loss	4p loss	5q loss	8p loss	9p loss	13q loss	17p loss	18q loss
No. of patients	130	47	47	51	30	50	57	77	55
Age
Mean	60	61	63	63	63	64	63	63	63
± SD	± 12.60	± 10.18	± 10.49	± 9.28	± 10.24	± 10.28	± 10.43	± 10.94	± 11.20
P		0.290	0.029	0.014	0.102	0.003	0.030	< 0.0001	0.030
Sex
Male	86	37	34	36	18	37	42	52	36
Female	44	10	13	15	12	13	15	25	19
P		0.033	0.335	0.450	0.510	0.182	0.136	0.710	1.000
Tumor location
Cardia	13	4	3	5	1	2	5	8	3
Body	48	16	16	13	10	14	16	24	16
Antrum	69	27	28	33	19	34	36	45	36
P		0.743	0.424	0.078	0.267	0.018	0.119	0.253	0.043
Histologic type
Intestinal	54	19	19	23	13	22	20	36	27
Diffuse	32	9	9	6	5	8	15	11	7
Mixed	44	19	19	22	12	20	22	30	21
P		0.395	0.395	0.018	0.480	0.176	0.404	0.004	0.026
Tumor size
Mean	5.3	5.8	5.1	4.9	5.1	4.9	5.7	5.2	5.5
± SD	± 3.01	± 2.86	± 2.64	± 2.29	± 2.42	± 2.73	± 3.02	± 2.86	± 3.13
P		0.129	0.631	0.131	0.705	0.181	0.179	0.564	0.483
Stage
I & II	64	20	21	20	14	22	21	36	24
III & IV	66	27	26	31	16	28	36	41	31
P		0.277	0.469	0.075	0.836	0.372	0.014	0.593	0.292
Recurrence
Peritoneal	24	10	9	8	5	10	12	16	11
Lymph node	10	4	3	3	2	5	4	6	3
Hematogenous	22	13	11	14	8	11	14	15	10
Total	56	27	23	25	15	26	30	37	24
P		0.422	0.507	0.070	0.428	0.826	0.415	0.899	0.663
Vital status	119	42	41	47	29	44	51	68	48
Alive	70	19	21	26	16	20	24	36	27
Dead	49	23	20	21	13	24	27	32	21
P		0.021	0.152	0.330	0.402	0.019	0.019	0.094	0.389

ISSN: 1471-230X