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Table 4 Association of IL-1 B polymorphisms with chronic gastritis and gastric ulcer.

From: Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis

SNP

Model

Genotype

Gastritis

Ulcer

   

OR (95%CI)

p-value

OR (95%CI)

p-value

-511 T>C

Co-dominant

TT

1.0*

 

1.0*

 
  

TC

3.1 (1.4-6.8)

0.004

2.3 (0.7-7.6)

0.175

  

CC

2.5 (0.7-8.4)

0.148

5.0 (0.9-29.0)

0.075

 

Dominant

TT

1.0*

 

1.0*

 
  

TC/CC

3.0 (1.4-6.3)

0.003

2.6 (0.8-8.2)

0.094

-31C>T

Co-dominant

CC

1.0*

 

1.0*

 
  

CT

2.3 (1.1-5.0)

0.035

2.6 (0.8-8.8)

0.112

  

TT

5.6 (1.8-17.6)

0.003

1.6 (0.2-12.6)

0.667

 

Dominant

CC

1.0*

 

1.0*

 
  

CT/TT

2.8 (1.3-5.8)

0.006

2.5 (0.8-7.9)

0.122

  1. * Reference category: healthy individuals. Models adjusted by age, place of origin, education, smoking habit, family history of gastritis or gastric ulcer, and H. pylori infection.
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BMC Gastroenterology

ISSN: 1471-230X

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