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Table 4 Association of IL-1 B polymorphisms with chronic gastritis and gastric ulcer.

From: Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis

SNP Model Genotype Gastritis Ulcer
    OR (95%CI) p-value OR (95%CI) p-value
-511 T>C Co-dominant TT 1.0*   1.0*  
   TC 3.1 (1.4-6.8) 0.004 2.3 (0.7-7.6) 0.175
   CC 2.5 (0.7-8.4) 0.148 5.0 (0.9-29.0) 0.075
  Dominant TT 1.0*   1.0*  
   TC/CC 3.0 (1.4-6.3) 0.003 2.6 (0.8-8.2) 0.094
-31C>T Co-dominant CC 1.0*   1.0*  
   CT 2.3 (1.1-5.0) 0.035 2.6 (0.8-8.8) 0.112
   TT 5.6 (1.8-17.6) 0.003 1.6 (0.2-12.6) 0.667
  Dominant CC 1.0*   1.0*  
   CT/TT 2.8 (1.3-5.8) 0.006 2.5 (0.8-7.9) 0.122
  1. * Reference category: healthy individuals. Models adjusted by age, place of origin, education, smoking habit, family history of gastritis or gastric ulcer, and H. pylori infection.
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