Table 1 Associations of GHRL and GHSR polymorphisms with colorectal cancer risk in the Czech population

GHRL

rs26802

G/G

286

278

1

G/T

294

245

1.18(0.92-1.51)

0.18

T/T

93

74

1.19(0.82-1.70)

0.25

0.16

rs27647

C/C

279

198

1

C/T

289

280

0.70(0.55-0.91)

0.008

T/T

93

110

0.57(0.40-0.80)

0.002

0.001

rs35683

A/A

204

147

1

A/C

331

297

0.80(0.61-1.05)

0.11

C/C

137

143

0.71(0.51-0.98)

0.04

0.02

rs4684677

A/A

601

523

1

A/C

78

74

0.91(0.64-1.30)

0.49

C/C

4

3

1.63(0.35-7.68)

0.62

0.70

rs696217

G/G

590

523

1

G/T

84

71

1.09(0.77-1.55)

0.64

T/T

4

6

0.60(0.16-2.18)

0.43

0.89

rs2075356

C/C

559

498

1

C/T

101

78

1.20(0.86-1.68)

0.63

T/T

7

7

0.88(0.30-2.61)

0.36

0.28

rs35684

A/A

257

248

1

A/G

213

174

1.10(0.84-1.43)

0.46

G/G

47

34

1.24(0.77-2.00)

0.36

0.29

GHSR

rs2922126

T/T

255

20

1

A/T

269

274

0.81(0.62-1.05)

0.11

A/A

74

39

1.48(0.95-2.30)

0.82

0.31

rs2944694

A/A

564

477

A/G

98

101

0.78(0.57-1.07)

0.14

G/G

7

11

0.46(0.16-1.28

0.14

0.08

rs495225

A/A

333

293

1

A/G

232

220

0.88 (0.68-1.13)

0.33

G/G

58

42

1.17(0.75-1.83)

0.47

0.77

rs572169

C/C

329

305

1

C/T

263

235

1.03(0.80-1.31)

0.80

T/T

57

48

1.14(0.74-1.74)

0.55

0.62