Table 7 Summary of complete eradication (CE) of BE and HGD post- endoscopic treatments
Study | CE rates of BE post -treatments (No. of patients who achieved CE of BE/No. of patients who received treatments) | CE rates of HGD post -treatments (No. of patients who achieved CE of HGD/No. of patients who received treatments) | ||
|---|---|---|---|---|
| Â | Up to 3 months | At 12 months | Up to 3 months | At 12 months |
PDT | ||||
ALA 15 mg/kg | 30.4% (7/23) 21.4-44.4%†| -** | No studies of HGD | No studies of HGD |
ALA 30 mg/kg | 43.9% (18/41) 14.3-50.0%†| -** | 100% (4/4) | -** |
ALA 40 mg/kg | 0% (0/2) | -** | 68.2% (15/22) 0-75.0%†| -** |
ALA 60 mg/kg | 19.2% (5/26) | -** | 96.6% (28/29) 96.3-100%†| -** |
HpD 1.5 mg/kg | 0% (0/5) | -** | 100% (1/1) | 100% (1/1) |
mTHPC 0.15 mg/kg | 16.7% (1/6) | -** | 66.7% (4/6) | -** |
Porfimer sodium (2 mg/kg) | 51.6% (94/182) 26.3-56.4%†| 15.4% (2/13) | 77.5% (62/80) | 100% (2/2) |
Other endoscopic treatments | ||||
APC | 85.5% (372/435) 0-100%†| 64.9% (50/77) 0-93.8%†| 85.7% (6/7) | 0% (0/0) |
Cryoablation | 81.8% (9/11) | 63.6% (7/11) | 100% (1/1) | -** |
Combined EMR & PDT | -** | -** | 66.7 (2/3) | -** |
Thermocoagulation | 100% (13/13) | -** | No studies of HGD | No studies of HGD |
EMR | 100% (1/1) | -** | 96.3% (26/27) 92.9-100%†| 83.3% (10/12) |
Laser ablation | 77.3% (58/75) 22.2-100%†| -** | -** | -** |
MPEC | 88.5% (23/26) | 100% (10/10) | No studies of HGD | No studies of HGD |
RFA | 69.0% (118/171) 21.9-97.7%†| 72.3% (170/235) 46.2%-92.6%†| 90.3% (93/103) 90.2-90.9%†| 81.0% (34/42) |