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Table 3 Number of 16S rRNA gene copies detected.

From: Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes

   IBS*    IBS-D**   
qPCR assay (m) Probiotic
(n = 22)
Placebo
(n = 20)
P Probiotic
(n = 11)
Placebo
(n = 8)
P
Bacteroides intestinalis-like 0 2.33 ± 0.69 2.65 ± 0.77 0.61 2.21 ± 0.80 1.52 ± 0.37 0.24
  3 2.49 ± 0.81 2.02 ± 0.60 0.52 2.38 ± 1.12 1.43 ± 0.60 0.20
  6 2.53 ± 0.81 2.30 ± 0.74 0.92 2.45 ± 1.14 1.19 ± 0.51 0.11
Clostridium cocleatum 88% 0 5.17 ± 0.73 4.98 ± 0.95 0.72 5.03 ± 1.03 4.07 ± 1.66 0.23
  3 5.06 ± 0.79 5.11 ± 0.95 0.93 5.07 ± 1.03 4.52 ± 1.81 0.53
  6 5.14 ± 0.72 4.92 ± 0.85 0.72 5.39 ± 0.99 4.56 ± 1.65 0.33
Clostridium thermosuccinogenes 85% 0 4.00 ± 0.55 3.94 ± 0.52 0.63 3.79 ± 0.63 3.52 ± 0.80 0.29
  3 5.05 ± 0.37 3.46 ± 0.39 0.00 4.88 ± 0.53 3.64 ± 0.47 0.01
  6 4.87 ± 0.41 3.91 ± 0.46 0.02 4.71 ± 0.67 3.54 ± 0.53 0.05
Collinsella aerofaciens-like 0 4.57 ± 0.63 4.14 ± 0.69 0.35 4.36 ± 0.96 3.13 ± 1.00 0.06
  3 4.33 ± 0.72 4.10 ± 0.71 0.70 3.91 ± 1.15 3.01 ± 0.96 0.25
  6 4.32 ± 0.68 4.45 ± 0.68 0.71 3.92 ± 1.06 3.79 ± 1.12 0.91
Coprococcus eutactus 97% 0 2.62 ± 0.73 2.99 ± 0.69 0.84 2.95 ± 1.26 2.49 ± 0.53 0.28
  3 2.75 ± 0.65 2.94 ± 0.69 0.94 3.42 ± 1.10 2.63 ± 1.02 0.20
  6 2.77 ± 0.60 3.03 ± 0.64 0.85 3.15 ± 0.97 2.53 ± 0.78 0.22
Ruminococcus torques 91% 0 4.29 ± 0.36 4.27 ± 0.32 0.93 4.17 ± 0.44 4.36 ± 0.47 0.60
  3 4.22 ± 0.28 4.34 ± 0.40 0.64 4.10 ± 0.42 4.54 ± 0.70 0.23
  6 4.05 ± 0.39 4.05 ± 0.40 1.00 3.73 ± 0.61 4.21 ± 0.53 0.19
Ruminococcus torques 93% 0 5.17 ± 0.20 5.39 ± 0.17 0.19 5.04 ± 0.27 5.45 ± 0.30 0.09
  3 5.25 ± 0.17 4.42 ± 0.26 0.00 5.37 ± 0.28 4.70 ± 0.41 0.00
  6 5.00 ± 0.36 4.50 ± 0.20 0.00 4.73 ± 0.64 4.57 ± 0.15 0.50
Ruminococcus torques 94% 0 3.54 ± 0.61 4.14 ± 0.53 0.10 3.69 ± 0.87 4.75 ± 0.49 0.04
  3 3.48 ± 0.60 3.97 ± 0.57 0.30 3.48 ± 0.92 4.42 ± 0.90 0.14
  6 3.06 ± 0.61 4.07 ± 0.43 0.02 2.72 ± 0.90 4.41 ± 0.66 0.01
  1. * Number of 16 S rRNA gene copies detected from 25 ng of faecal DNA at each time-point analysed and the p-values for linear model comparisons of probiotic and placebo groups as a whole. The values are presented as log10 averages for each time-point (0, 3 and 6 months). Significant p-values (P < 0.5) are indicated in bold.
  2. ** Number of 16 S rRNA gene copies detected from 25 ng of faecal DNA at each time-point analysed and the p-values for linear model comparisons for diarrhoea-predominant (IBS-D) subjects. The values are presented as log10 averages for each time-point (0, 3 and 6 months). Significant p-values (P < 0.5) are indicated in bold.