Role of tight junction proteins in gastroesophageal reflux disease

BMC Gastroenterology

Table 3 Histopathological parameters

	Controls	NERD	ERD	P-value One way ANOVA
*Activity*	0 ± 0	0.23 ± 0.54	0.22 ± 0.41	n.s.
*Chronicity*	0.72 ± 0.54	0.97 ± 0.51	1.05 ± 0.67	n.s.
*Basal cell hyperplasia [BSH]*	0.52 ± 0.59	1.11 ± 0.63	1.42 ± 0.84	<0.001
*Papillary elongation [PE]*	1.32 ± 0.80	1.71 ± 0.86	2.07 ± 0.85	<0.001
*Dilated intercellular spaces [ICS]*	0.72 ± 0.68	1.49 ± 1.01	2.10 ± 0.13	<0.001

Parameters were scored semiquantitatively as described in “Patients and Methods”. Data are presented as mean ± sd.

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