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Table 4 Comparison of major adverse events between the three treatment options

From: Comparison of vonoprazan dual therapy, quadruple therapy and standard quadruple therapy for Helicobacter pylori infection in Hainan: a single-center, open-label, non-inferiority, randomized controlled trial

 

Group-V1 (n = 43)

Group-V2 (n = 41)

Group-V3 (n = 43)

P Value

H

Overall

1 (2.3%)

8 (19.5%)

6 (14.0%)

< 0.05

6.189

Skin eruption

0

1 (2.4%)

0

0.350

2.098

Nausea

1 (2.3%)

6 (14.6%)

1 (2.3%)

< 0.05

7.070

Dizziness

1 (2.3%)

2 (4.9%)

1 (2.3%)

0.745

0.588

Inappetence

0

1 (2.4%)

0

0.350

2.098

Abdominal pain

0

0

3 (7.0%)

0.051

5.955

Abdominal bloating

0

0

1 (2.3%)

0.377

1.953

Constipation

0

0

1 (2.3%)

0.377

1.953

Easy fatigability

0

1 (2.4%)

0

0.350

2.098