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Table 5 Adverse events in patients

From: Evaluation of models to predict prognosis in patients with advanced hepatocellular carcinoma treated with TACE combined with apatinib

Adverse events

patients (n = 200)

grade1(n%)

Grade2(n%)

Grade3(n%)

grade4(n%)

Hand and foot syndrome

45(22.50%)

38(19.00%)

32 (16.00%)

8(4.00%)

Hypertension

25(12.50%)

20(10.00%)

18 (9.00%)

7(3.50%)

Proteinuria

17(8.50%)

15(7.50%)

14 (7.00%)

3(1.50%)

Alopecia

5(2.50%)

4(2.00%)

1 (0.50%)

0

Fatigue

27(13.50%)

13(6.50%)

8 (4.00%)

1(0.50%)

Decreased appetite

23(11.50%)

11(5.50%)

14 (7.00%)

2(1.00%)

Diarrhea

15(7.50%)

11(5.50%)

3 (1.50%)

0

Oral mucositis

34(17.00%)

21(10.50%)

6 (3.00%)

1(0.50%)

hoarseness

6(3.00%)

4(2.00%)

7 (3.50%)

0

Abdominal pain

31(15.50%)

17(8.50%)

7 (3.50%)

1(0.50%)

Hematotoxicity

14(7.00%)

13(6.50%)

6 (3.00%)

2(1.00%)

Rash

21(10.50%)

15(7.50%)

7 (3.50%)

1(0.50%)

Vomiting

11(5.50%)

9(4.50%)

5 (2.50%)

0

constipation

1(0.50%)

2 (1.00%)

2 (1.00%)

0

headache

11(5.50%)

10(5.00%)

4 (2.00%)

1(0.50%)

Liver dysfunction

3(1.50%)

4(2.00%)

3 (1.50%)

0

Gastrointestinal hemorrhage

1(0.50%)

2(1.00%)

1 (0.50%)

0