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Table 3 Cough manometric parameters comparing 25 healthy (female x male)

From: London Protocol under water-perfused HRM in a healthy population, towards novel 3D manometric parameters in an evaluation of anorectal functional disorders

Cough manometric parameters

Female (25)

Male (25)

p

Mean (SD)

Med (IQR)

Mean (SD)

Med (IQR)

London Protocol parameters

Maximum pressure anal canal (mmHg)r

132 (31.6)

134.6 [127.6;155.0]

150.7 (28.8)

150.2 [124.9;171.6]

<0.05

Maximum pressure rectum (mmHg)

65.5 (23.8)

65.0 [47.0;79.3]

87.0 (27.3)

82.2 [72.5;95.5]

<0.01

Complementary parameters

Anorectal gradient pressure (mmHg)

67.7 (22.1)

62.6 [48.6;83.9]

63.7 (26.8)

63.1 [55.7;71.9]

0.57

3D parameters

Anal canal PV in cough (104mmHg².cm)

11.0 (4.8)

10.6 [8.3;14.0]

15.1 (5.2)

15.3 [11.6;18.2]

<0.01

Highest pressure asymmetry (%); anal canal

14.4 (5.9)

13.9 [10.0;16.9]

16.0 (6.7)

14.9 [10.8;20.3]

0.39

Lowest pressure asymmetry (%); anal canal

14.7 (4.9)

14.9 [12.6;18.1]

12.5 (4.0)

11.7 [8.9;15.0]

0.08

  1. SD Standard deviation, Med Median, IQR Interquartile range),PV Pressure-volume
  2. Bold values indicate statistically significant (p < 0.05)