Characteristic | HCC+ (n = 12) | HCC- (n = 119) | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|---|---|
odds ratio | 95%CI | p | odds ratio | 95%CI | p | |||
autoimmune hepatitis | 10 | 77 | 2.73 | 0.68–18.28 | 0.17 | |||
elderly (≥ 65) | 7 | 55 | 1.63 | 0.49–5.78 | 0.42 | |||
liver cirrhosis at diagnosis | 11 | 25 | 41.36 | 7.52-774.05 | < 0.05 | 39.93 | 5.72-845.26 | < 0.0001 |
male | 4 | 15 | 3.47 | 0.93–12.93 | 0.08 | |||
history of hepatitis virus | 0 | 9 | - | - | 0.18 | |||
duration of autoimmune hepatitis (≥ 10years) | 3 | 29 | 1.03 | 0.26–4.08 | 0.96 | |||
steroid use | 8 | 64 | 1.72 | 0.49–6.18 | 0.39 | |||
fatty liver | 4 | 33 | 1.30 | 0.37–4.62 | 0.69 | |||
alcohol | 3 | 13 | 2.72 | 0.65–11.33 | 0.20 | |||
diabetes | 5 | 14 | 5.36 | 1.50-19.19 | < 0.05 | 4.58 | 0.60-42.77 | 0.14 |
history of blood transfusions | 1 | 5 | 2.07 | 0.22–19.36 | 0.55 | |||
obesity | 5 | 33 | 1.86 | 0.55–6.28 | 0.33 | |||
Fib-4 index (≥ 2.67) | 10 | 74 | 3.04 | 0.64–14.51 | 0.12 | |||
ALT one year after diagnosis (≥ 31 IU/L) | 7 | 27 | 5.44 | 1.40-26.75 | < 0.05 | 3.12 | 0.56–21.46 | 0.21 |
IgG one year after diagnosis (≥ 1701 mg/dL) | 4 | 21 | 2.33 | 0.64–8.47 | 0.21 | |||
Fib-4 index one year after diagnosis(2.67≦) | 7 | 20 | 8.17 | 1.93–34.50 | < 0.05 | 2.13 | 0.36–13.79 | 0.40 |