Table 1 Clinicopathologic characteristics of patients and hepatic observations

Patient (n = 460)

460

302

158

Mean age (years) *

54.24 ± 11.32

56.05 ± 9.65

50.75 ± 13.31

Sex

Male

347 (75.4%)

257 (85.1%)

90 (57.0%)

Female

113 (24.6%)

45 (14.9%)

68 (43.0%)

BMI

23.6 (21.3–25.4)

23.3 (20.9–24.4)

23.7 (21.8–26.0)

Cirrhosis

Presence

280 (60.9%)

191(63.2%)

89 (56.3%)

Absence

180 (39.1%)

111 (36.8%)

69 (43.7%)

Cause of liver disease

Hepatitis B virus

368 (78.0%)

253 (81.6%)

115 (71.0%)

Hepatitis C virus

62 (13.1%)

37 (11.9%)

25 (15.4%)

Alcohol

29 (6.1%)

11 (3.5%)

18 (11.1%)

NASH

13 (2.8%)

9 (2.9%)

4 (2.5%)

Child–Pugh Class

Class A

386 (83.9%)

247 (81.8%)

139 (88.0%)

Class B

60 (13.0%)

42 (13.9%)

18 (11.4%)

Class C

14 (3.0%)

13 (4.3%)

1 (0.6%)

Hepatic function index**

AST

20.4 (29–50.7)

29.3 (20.9–52)

28.3 (18.5–40.1)

ALT

29.6 (21.9–47.9)

30.3 (23-48.6)

28.1 (20.6–46.8)

TBIL (µmol/L)

13.6 (9.9–20.2)

14.7 (11.1–20.5)

12.1 (8.8–17.5)

PT

12.3 (11.6–13.5)

12.3 (11.7–13.5)

12.2 (11.4–13.6)

PLT

143.7 (95.0–194.5)

140.0(91.0–183.0)

152.5 (111.8-218.7)

AFP**

5.83(2.7–43.1)

13.1(3.3–143.8)

3.1(1.9–5.98)

Lesions(n = 473)

473

311

162

No. of nodules

1

447 (94.5%)

293(94.2%)

154 (95.1%)

2

13 (6.6%)

9 (2.9%)

4 (2.5%)

Mean size (cm)

2.91 ± 2.33

3.34 ± 1.75

2.08 ± 1.75

Degree of differentiation of HCC

Well differentiated

54 (17.4%)

Moderately differentiated

161 (51.8%)

Low-differentiated

96 (30.9%)

Standard reference of diagnosis

Pathologic diagnosis

355 (75.1%)

311 (100%)

44 (27.2%)

Typical imaging features with size stability

118 (24.9%)

0 (0%)

118 (76.6%)