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Table 1 Baseline (at the initiation of TDF treatment) characteristics of the 103 patients

From: Successful therapy with tenofovir disoproxil fumarate (TDF) in patients with chronic hepatitis B (CHB) does not guarantee amelioration of liver damage assessing by transient elastography. A retrospective - prospective multicenter study

Baseline patients’ characteristics

(N = 103)

Age, years*

> 60 years old, n (%)

56.7 ± 13

44 (43%)

Male patients, n (%)

58 (56%)

HBeAg– positive, n (%)

8 (7.8%)

Baseline liver stiffness (kPa)*

8.7 ± 6.2

Advanced fibrosis / cirrhosis n (%)

Cirrhosis n (%)

25 (24%)

14 (14%)

Treatment duration with TDF**, months

90 (36–154)

ALT (IU/L)**

36.9 (11-2130)

HBV DNA (log10 IU/L)**

4.8 (2.3–8.8)

Platelet x 109 /L**

200 (57–337)

BMI (Kg/m2)*

≥ 25Kg/m2, n (%)

≥ 30 Kg/m2, n (%)

25 ± 4

46 (45%)

10 (10%)

Diabetes Mellitus, n (%)

10 (10%)

Hypertension, n (%)

29 (28%)

Dyslipidemia, n (%)

11 (11%)

Metabolic syndrome, n (%)

47 (46%)

Active smokers, n (%)

21 (20%)

  1. *mean ± SD, ** median (range)