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Table 2 Intraoperative data of patients

From: Safety and efficacy of a low-dose combination of midazolam, alfentanil, and propofol for deep sedation of elderly patients undergoing ERCP

Parameter

Age 50–64

n = 202

Age 65–79

n = 216

Age ≥ 80

n = 192

P-Value

procedure duration (min)

66.4 ± 14.8

67.5 ± 9.3

68.8 ± 13.1

0.174

total dose of propofol (mg/kg)

5.6 ± 0.9

4.4 ± 0.4

4.3 ± 0.6

P < 0.001

total dose of alfentanil (µg/kg)

11.6 ± 1.5

10.6 ± 0.8

10.7 ± 1.1

P < 0.001

total dose of midazolam (mg)

1

1

1

-

Time to awake (min)

5.7 ± 2.4

5.3 ± 1.8

5.5 ± 1.5

0.083

Hypotension

9 (4.5)

4 (1.9)

10 (5.2)

0.170

Hypoxemia

7 (3.5)

5 (2.3)

9 (4.7)

0.423

Other complications *

0 (0.0)

0 (0.0)

0 (0.0)

-

  1. Data are presented as mean ± standard deviation or number (percentage)
  2. BMI Body mass index, ASA American society of anesthesiologists, SBP Systolic blood Pressure, DBP Diastolic blood pressure, HR Heart rate, SpO2 Saturation of Peripheral Oxygen, BIS Bispectral Index
  3. *: hypertension, bradycardia, tachycardia, respiratory depression, nausea and vomiting