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Table 4 Basic characteristics of participants according to train and second validation set

From: Using new indices to predict metabolism dysfunction-associated fatty liver disease (MAFLD): analysis of the national health and nutrition examination survey database

Characteristic

Train Set,

N = 8858(40%)1

Validation2,

N = 2299(60%)1

p-value2

Sex

  

0.6

Male

4,354(49%)

1,143(50%)

 

FeMale

4,504(51%)

1,156(50%)

 

Age

46 (32, 60)

47 (32, 61)

0.8

BMI (kg/m2)

28 (24, 32)

28 (25, 33)

0.015

Ratio of income to poverty

2.81 (1.37, 4.81)

3.19 (1.58, 5.00)

0.014

Race

  

0.5

Mexican American

1,441(8.9%)

323(9.3%)

 

Other Hispanic

1,014(6.0%)

216(6.7%)

 

Non-Hispanic White

3,704(67%)

798(64%)

 

Non-Hispanic Black

1,734(10%)

504(10%)

 

Other Race

965(7.6%)

458(10%)

 

AIP

-0.05 (0.34)

0.01 (0.32)

 < 0.001

MAFLD

  

 < 0.001

NO

6,044(68%)

1,318(58%)

 

YES

2,814(32%)

981(42%)

 

AGTR

2.26 (1.48, 3.13)

2.11 (1.38, 3.00)

 < 0.001

UHR

0.10 (0.07, 0.14)

0.10 (0.07, 0.14)

0.9

TC (mmol/l)

1.15 (0.79, 1.72)

1.32 (0.88, 1.94)

 < 0.001

CRE(umol/L)

325 (83)

322 (86)

0.3

WC (cm)

99 (16)

101 (17)

0.045

Hypertension, n (%)

  

0.6

NO

5,798(68%)

1,453(69%)

 

YES

3,060(32%)

846(31%)

 

Overweight/Obesity

  

0.028

NO

2,738(31%)

626(27%)

 

YES

6,120(69%)

1,673(73%)

 

Activity

  

 < 0.001

Light

2,222(21%)

545(19%)

 

Moderate

3,472(39%)

769(33%)

 

Vigorous

3,164(39%)

985(49%)

 

ALB(g/L)

  

 < 0.001

Mean (SD)

42.8 (3.3)

41.1 (3.3)

 

Drinking

  

 < 0.001

Never

2,314(21%)

665(21%)

 

Moderate

862(10%)

852(39%)

 

Excessive

5,682(69%)

782(40%)

 

ALP(U/L)

63 (52, 77)

73 (59, 89)

 < 0.001

ALT(U/L)

21 (16, 29)

18 (13, 27)

 < 0.001

Diabetes, n (%)

  

0.3

NO

7,821(91%)

1,981(90%)

 

YES

1,037(9.2%)

318(10%)

 

Smoking

  

0.14

NO

4,910(55%)

1,353(57%)

 

YES

3,948(45%)

946(43%)

 

Protein (gm)

83 (34)

82 (37)

0.5

Vitamin C (mg)

64 (30, 114)

59 (27, 105)

0.013

Mercury, total (umol/L)

7 (11)

7 (11)

0.4

Blood cadmium (nmol/L)

4.5 (5.4)

3.9 (5.2)

0.010

  1. AGTR Albumin to glutamyl transpeptidase ratio, AIP Plasma atherogenicity index, UHR Serum uric acid to high-density lipoprotein cholesterol ratio
  2. 1n (unweighted)(%); Median (IQR)
  3. 2chi-squared test with Rao & Scott's second-order correction; Wilcoxon rank-sum test for complex survey samples; t-test adapted to complex survey samples