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Table 1 Baseline data of patients with combined ANHC about demographic and clinical characteristics of tumor and therapy

From: Prediction of survival and analysis of prognostic factors for patients with AFP negative hepatocellular carcinoma: a population-based study

Variables

Total Cohort

Training Cohort

Validation Cohort

All Patient

1811

1267

544

Age at diagnosis

   

 <55

355(19.6)a

237(18.7)

118(21.7)

 ≥55

1456(80.4)

1030(81.3)

426(78.3)

Ethnicity

   

 Caucasian

1171(64.7)

821(64.8)

350(64.3)

 African–American

167(9.2)

124(9.8)

43(7.9)

 Others

473(26.1)

322(25.4)

151(27.8)

Gender

   

 Male

1409(77.8)

980(77.3)

429(78.9)

 Female

402(22.2)

287(22.7)

115(21.1)

Year of Diagnosis

   

 After 2009

1054(58.6)

729(57.5)

325(59.7)

 Before 2009

757(41.4)

538(42.5)

219(40.3)

Grade

   

 Grade I

731(40.4)

506(39.9)

225(41.4)

 Grade II

853(47.1)

597(47.1)

256(47.1)

 Grade III

210(11.6)

151(11.9)

59(10.8)

 Grade IV

17(0.9)

13 [1]

4(0.7)

TNM Stage

   

 I

992(54.8)

681(53.7)

311(57.2)

 II

358(19.8)

262(20.7)

96(17.6)

 III

328(18.1)

228 [18]

100(18.4)

 IV

133(7.3)

96(7.6)

37(6.8)

Surgery

   

 No surgery

736(40.6)

521(41.1)

215(39.5)

 Liver Resection

816(45.1)

566(44.7)

250(46)

 Liver Transplant

259(14.3)

180(14.2)

79(14.5)

Chemotherapy

   

 No/Unknown

1251(69.1)

870(68.7)

381(70)

 Yes

560(30.9)

397(31.3)

163 [30]

Radiation

   

 No/unknown

1697(93.7)

1194(94.2)

503(92.5)

 Yes

114(6.3)

73(5.8)

41(7.5)

Marital Group

   

 Married

1099(60.7)

761(60.1)

338(62.1)

 Single/divorced/widowed

712(39.3)

506(39.9)

206(37.9)

Tumor Size

   

 <5 cm

1011(55.8)

702(55.4)

309(56.8)

 ≥5 cm

800(44.2)

565(44.6)

235(43.2)

  1. a The numbers outside and in every parentheses correspond to the number of patients (n) and the percentage of the respective group (%)