Fig. 3
From: The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models
Immunological and Pathological Response to Low-Dose IL-2 Therapy in PBC Mouse Models. (A) Flow cytometric evaluation indicating a reduction in Th17 and an elevation in Treg populations within PBC mouse livers post low-dose IL-2 treatment. (B) H&E staining and CK-19 immunohistochemistry of liver sections post low-dose IL-2 treatment. Th17 cell hepatic infiltration following low-dose IL-2 therapy in PBC mouse models (magnification: ×200). (C) Biochemical serum parameter analysis post low-dose IL-2 intervention in control and PBC mouse models. (D) Serum Th17- and Treg-related cytokine levels following low-dose IL-2 therapy in control versus PBC mouse models