Table 2 The impact of clinical and pathological characteristics on lymphocyte subsets

Age

 <65

37.68 ± 9.65

0.088

30.98 ± 10.63

0.399

1.42 ± 0.71

0.984

19.95 ± 10.33

0.017

5.84 ± 2.42

0.369

7.52 ± 3.46

0.207

 ≥ 65

35.28 ± 9.51

29.64 ± 11.12

1.42 ± 0.82

23.38 ± 11.01

6.26 ± 4.07

6.89 ± 3.35

Gender

 Female

38.69 ± 11.01

0.078

29.55 ± 11.03

0.480

1.51 ± 0.72

0.299

20.35 ± 11.94

0.524

5.81 ± 2.17

0.605

7.42 ± 3.21

0.709

 Male

35.97 ± 8.99

30.78 ± 10.76

1.39 ± 0.77

21.44 ± 10.27

6.08 ± 3.49

7.21 ± 3.51

BMI

 BMI<18.5 kg/m2

37.99 ± 9.15

0.393

28.08 ± 9.91

0.154

1.62 ± 0.92

0.088

21.04 ± 10.31

0.949

6.31 ± 5.37

0.529

7.54 ± 3.28

0.597

 BMI ≥ 18.5 kg/m2

36.44 ± 9.75

30.96 ± 10.97

1.38 ± 0.71

21.16 ± 10.86

5.94 ± 2.48

7.21 ± 3.46

Smoking history

 No

35.74 ± 9.99

0.123

31.47 ± 11.08

0.146

1.35 ± 0.77

0.140

20.76 ± 11.33

0.588

5.99 ± 3.94

0.963

7.02 ± 3.67

0.271

 Yes

37.88 ± 9.13

29.21 ± 10.43

1.51 ± 0.74

21.60 ± 10.03

6.02 ± 1.93

7.57 ± 3.11

Drinking history

 No

36.43 ± 9.80

0.494

31.03 ± 11.54

0.233

1.40 ± 0.76

0.548

21.16 ± 11.23

0.961

5.89 ± 3.54

0.408

7.09 ± 3.47

0.245

 Yes

37.49 ± 9.26

28.91 ± 8.59

1.47 ± 0.76

21.08 ± 9.43

6.31 ± 1.92

7.73 ± 3.28

Extensive metastasis

 No

36.87 ± 10.39

0.856

30.57 ± 11.24

0.893

1.45 ± 0.84

0.620

20.73 ± 10.84

0.663

6.23 ± 3.94

0.423

7.37 ± 3.58

0.730

 Yes

36.62 ± 9.15

30.35 ± 10.58

1.40 ± 0.70

21.42 ± 10.71

5.85 ± 2.56

7.20 ± 3.33

PD-L1 expression

 CPS<5

35.49 ± 8.96

0.055

32.17 ± 11.56

0.015

1.30 ± 0.71

0.024

20.89 ± 10.50

0.728

6.00 ± 3.61

0.977

7.02 ± 3.03

0.277

 CPS ≥ 5

38.15 ± 10.24

28.42 ± 9.56

1.55 ± 0.78

21.43 ± 11.06

6.01 ± 2.61

7.56 ± 3.83

Mismatch repair status

 pMMR

36.89 ± 9.68

0.269

30.54 ± 10.89

0.566

1.43 ± 0.76

0.709

21.03 ± 10.90

0.519

5.93 ± 3.18

0.165

7.24 ± 3.44

0.533

 dMMR

33.24 ± 8.49

28.41 ± 9.62

1.33 ± 0.64

23.40 ± 6.29

7.44 ± 3.10

7.97 ± 3.16