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Table 2 Coexisting extra-intestinal symptoms of male and female patients with IBS-D

From: Gender differences in gastrointestinal, biopsychosocial and healthcare-seeking behaviors in Chinese patients with irritable bowel syndrome predominant with diarrhea

Variables

Male

(n = 299) (95% CI)

Female

(n = 191) (95% CI)

P value

GERD (%)

153 (48.8) (45.5–56.9)

96 (50.3) (43.1–57.4)

0.844

Heartburn (%)

90 (30.1) (24.9–35.3)

61 (31.9) (25.3–38.6)

0.668

Acid reflux (%)

107 (35.8) (30.3–41.3)

75 (39.3) (32.3–46.3)

0.437

Food regurgitation (%)

48 (16.1) (11.9–20.2)

18 (9.4) (5.2–13.6)

0.036*

Retrosternal chest pain (%)

27 (9.0) (5.8–12.3)

10 (5.2) (2.0-8.4)

0.121

Functional dyspepsia (%)

174 (58.2) (52.6–63.8)

113 (59.2) (33.2–44.5)

0.832

Epigastric pain syndrome (%)

103 (34.4) (29.0-39.9)

72 (37.7) (30.8–44.6)

0.464

Epigastric pain (%)

89 (29.8) (24.6–35)

66 (34.6) (27.7–41.4)

0.266

Epigastric burning (%)

38 (12.7) (8.9–16.5)

23 (12.0) (7.4–16.7)

0.827

Postprandial distress syndrome (%)

132 (44.1) (38.5–49.8)

87 (45.5) (38.4–52.7)

0.761

Postprandial fullness (%)

117 (39.1) (33.6–44.7)

77 (40.3) (33.3–47.3)

0.794

Early satiation (%)

44 (14.7) (10.7–18.8)

34 (17.8) (12.3–23.3)

0.363

Headache (%)

132 (44.1) (38.5–49.8)

100 (52.4) (45.2–59.5)

0.076

Frequent micturition (%)

111 (37.1) (31.6–42.6)

52 (27.2) (20.9–33.6)

0.023*

Dyspareunia (%)

101 (33.8) (28.4–39.2)

71 (37.2) (30.3–44.1)

0.443

  1. IBS-D, irritable bowel syndrome predominant with diarrhea; GERD, gastroesophageal reflux disease; CI, confidence interval
  2. Data presented as number (%) (95% CI). Chi-square test. *P < 0.05