Variables | Total (N = 289) | Non-encapsulation (N = 209) | Early encapsulation (N = 80) | p value |
---|---|---|---|---|
Demographic | ||||
Age (years) | 45.0(35.0–57.0) | 43.0(35.0–57.0) | 47.0(39.0–55.0) | 0.645 |
Gender (male%) | 64.0(185/289) | 67.0(140/209) | 56.2(45/80) | 0.089 |
Body mass index (kg/m2) | 25.7(23.4–28.4) | 26.1(24.0–29.3) | 24.1(22.7–26.0) | 0.173 |
Comorbidity (%) | ||||
Diabetes | 30.4(88/289) | 32.1(67/209) | 26.2(21/80) | 0.337 |
Hypertension | 30.8(89/289) | 33.5(70/209) | 23.8(19/80) | 0.108 |
Etiology (%) | ||||
Biliary | 40.8(118/289) | 41.6(87/209) | 38.8(31/80) | 0.656 |
Hypertriglyceridemia | 41.5(120/289) | 41.6(87/209) | 41.2(33/80) | 0.954 |
Alcoholic | 7.6(22/289) | 7.2(15/209) | 8.8(7/80) | 0.652 |
others | 10.0(29/289) | 9.6(20/209) | 11.2(9/80) | 0.671 |
Time from onset to CECT examination (day) | 7.3(6.4–8.4) | 7.0(6.1–8.1) | 8.0(7.0–8.6) | < 0.001* |
Laboratory indicator | ||||
Blood amylase (U/L) | 524.0(222.5–1090.5) | 518.5(228.2–1084.2) | 599.0(115.0–1144.0) | 0.584 |
White blood cell (× 109/L) | 11.6(8.7–15.4) | 11.6(8.9–15.4) | 11.6(7.8–15.2) | 0.190 |
Platelet (× 109/L) | 174.0(131.0–211.0) | 171.0(123.0–211.0) | 185.5(139.8–218.2) | 0.208 |
C-reactive protein (mg/L) | 247.0(155.0–310.2) | 259.0(162.8–317.0) | 207.4(152.0–285.0) | 0.033* |
Procalcitonin (ng/mL) | 2.0(0.8–4.9) | 2.5(1.0–5.8) | 0.9(0.5–2.0) | 0.059 |
Lactate (mmol/L) | 1.9(1.4–2.8) | 1.9(1.5–2.9) | 1.9(1.3–2.7) | 0.888 |
Alanine aminotransferase (U/L) | 21.0(14.0–42.0) | 23.5(16.0–49.2) | 17.5(13.0–28.5) | 0.017* |
Pro-albumin (g/L) | 123.5(85.0–166.5) | 122.0(85.0–161.2) | 132.0(89.5–179.8) | 0.055 |
Albumin (g/L) | 32.0(29.0–35.0) | 33.0(29.0–35.0) | 32.0(29.5–35.5) | 0.958 |
Total bilirubin (μmol/L) | 21.5(15.3–31.2) | 23.1(16.6–32.2) | 17.7(12.1–24.8) | 0.037* |
Creatinine (μmol/L) | 67.0(54.0–87.0) | 71.0(55.8–96.2) | 58.0(48.0–69.0) | 0.004* |
Fibrinogen (g/L) | 5.8(4.4–6.7) | 5.8(4.4–6.8) | 5.6(4.5–6.5) | 0.834 |
D-dimers (mg/L) | 4.7(3.1–7.5) | 4.9(3.3–8.5) | 4.6(2.7–6.8) | 0.090 |
Clinical scoring | ||||
APACHEII score | 8(6–11) | 8(6–11) | 8(5–9) | 0.012* |
CTSI score | 6(4–6) | 6(4–8) | 6(5–6) | 0.154 |
Pancreatic necrosis | 72.3(209/289) | 70.8(148/209) | 76.2(61/80) | 0.355 |
Outcomes | ||||
Infected pancreatic necrosis (%) | 12.5(36/289) | 14.8(31/209) | 6.2(5/80) | 0.075 |
Surgical intervention (%) | 13.8(40/289) | 16.3(34/209) | 7.5(6/80) | 0.053 |
Persistent organ failure(%) | 25.3(73/289) | 31.6(66/209) | 8.8(7/80) | < 0.001* |
In-hospital mortality(%) | 4.5(13/289) | 5.7(12/209) | 1.2(1/80) | 0.183 |