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Table 2 Comparison of clinicopathological factors between the NRF and RF groups

From: Predictive factors for esophageal stenosis in patients receiving prophylactic steroid therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma

Variable

NRF group

RF group

p-value

 

(n = 152)

(n = 59)

 

ESD history

  

0.101

    + 

26 (17.1)

16 (27.1)

 

    − 

126 (82.9)

43 (72.9)

 

CRT history

  

0.0233

    + 

8 (5.3)

9 (15.3)

 

    − 

144 (94.7)

50 (84.7)

 

Location

  

0.753

    Ce-Ut

33 (21.7)

14 (23.7)

 

    Mt-Ae

119 (78.3)

45 (76.3)

 

Macroscopic type

  

0.601

    0-Is/0-Iia

12 (7.9)

6 (10.2)

 

    0-IIb/0-Iic

140 (92.1)

53 (89.8)

 

Tumor size (mm), mean ± SD

34.4 ± 17.8

46.2 ± 20.3

 < 0.01

Resection area

  

 < 0.01

    Entire circumference

19 (12.5)

28 (47.5)

 

    Sub-circumference

133 (87.5)

31 (52.5)

 

Muscle layer damage

  

0.375

    + 

13 (8.6)

3 (5.1)

 

    − 

139 (91.4)

56 (94.9)

 

Prophylactic methods of stenosis

  

0.0649

    TrA injection only

70 (46.0)

19 (32.2)

 

    TrA injection + oral PSL

82 (54.0)

40 (67.8)

 

Pathological tumor depth

  

0.729

    pT1a

134 (88.2)

53 (89.8)

 

    pT1b

18 (11.8)

6 (10.2)

 

Additional CRT after ESD

  

0.225

    + 

22 (14.5)

5 (8.5)

 

    − 

130 (85.5)

54 (91.5)

 
  1. EBD Endoscopic balloon dilatation, ESD Endoscopic submucosal dissection, CRT Chemoradiation therapy, NRF Non-refractory, PSL Prednisolone, RF Refractory, SD Standard deviation, TrA Triamcinolone acetonide