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Table 1 Characteristics of patients with MASLD and healthy controls

From: Targeted metabolomics reveals plasma short-chain fatty acids are associated with metabolic dysfunction-associated steatotic liver disease

 

Healthy controls

(n = 50)

MASLD

(n = 100)

P-value

Sex (male)

27 (54%)

58 (58%)

0.77

Age, years

50 (14)

51 (15)

0.51

BMI, kg/m2

24 (2.7)

35 (6.7)

< 0.001

HbA1c, mmol/mol

35 (3.7)

47 (13)

< 0.001

ALT, U/L

21 (6.5)

87 (79)

< 0.001

LDL-C, mmol/L

2.7 (0.86)

2.4 (0.98)

0.046

VLDL-C, mmol/L

0.42 (0.17)

1.0 (0.57)

< 0.001

HDL-C, mmol/L

1.8 (0.52)

1.1 (0.29)

< 0.001

Triglycerides, mmol/L

0.92 (0.39)

2.4 (1.5)

< 0.001

Fibroscan®, kpa

4.4 (1.2)

13 (8.4)

< 0.001

CAP, dB/m

210 (28)

340 (47)

< 0.001

  1. Data presented as n (%) or mean values with standard deviations. MASLD, Metabolic dysfunction-associated steatotic liver disease; BMI, Body mass index; ALT, Alanine aminotransferase; LDL-C, Low-density lipoprotein cholesterol; VLDL-C, Very-low-density lipoprotein cholesterol; HDL-C, High-density lipoprotein cholesterol; CAP, Continuous attenuation factor