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Fig. 4 | BMC Gastroenterology

Fig. 4

From: The P2Y1 receptor in the colonic myenteric plexus of rats and its correlation with opioid-induced constipation

Fig. 4

Spontaneous contractive amplide and effects of MOR antagonists (EM2 and β-FNA) on the motility of circular muscle strips from the rat colon. (A-B) EM2 increased the amplitude, while β-FNA significantly suppressed EM2-evoked contractions (*P<0.05). (C-D) The β-FNA decreased the amplitude of spontaneous contractions(*P<0.05). Conversely, EM2 had no obvious effect on the inhibition of β-FNA (*P>0.05)

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