Fig. 1From: Evaluation of the causal effects of blood metabolites on irritable bowel syndrome: Mendelian randomizationThe study design of the correlation between blood metabolites and irritable bowel syndrome. Abbreviations: Assumption 1:the exposures of interest are significantly related to genetic instruments; Assumption 2: genetic tools are independent of confounding variables; Assumption 3: genetic tools are not linked to outcomes and only impact them through exposuresBack to article page