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Table 3 PPVs for toxic liver disease, hepatic failure without and with toxic liver disease with hepatic necrosis, and jaundice

From: Validation of diagnoses of liver disorders in users of systemic azole antifungal medication in Sweden

 

Evaluable patients

N

Confirmed diagnosis (true positive)

N

Non-confirmed diagnosis (false positives) N

PPV (95% CI)

Toxic liver disease

26

14

12

53.8% (33.4–73.4%)

Hepatic failure

    

Any hepatic failure

58

36

22

62.1% (48.4–74.5%)

Liver synthetic dysfunction

58

31

27

53.4% (39.9–66.7%)

Liver synthetic dysfunction with ascites

58

18

40

31.0% (19.5–44.5%)

International definition of hepatic failure

58

21

37

36.2% (24.0–49.9%)

Hepatic failure including toxic liver disease with hepatic necrosisa

Any hepatic failure

61

37

24

60.7% (47.3–72.9%)

Liver synthetic dysfunction

61

32

29

52.5% (39.3–65.4%)

Liver synthetic dysfunction with ascites

61

19

42

31.1% (19.9–44.3%)

International definition of hepatic failure

61

21

40

34.4% (22.7–47.7%)

Jaundice

31

30

1

96.8% (83.3–99.9%)

  1. a. Toxic liver disease with hepatic necrosis - ICD-10 code K71.1