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Table 4 Predictive performance of four IR indicators on hepatic steatosis, hepatic fibrosis

From: Association of insulin resistance indicators with hepatic steatosis and fibrosis in patients with metabolic syndrome

Variables

Indicators

AUC

(95%CI)

Sensitivity

(95%CI)

Specificity

(95%CI)

NPV

(95%CI)

PPV

(95%CI)

Accuracy (95%CI)

Hepatic steatosis

HOMA-IR

0.693

(0.656–0.730)

0.618

(0.578–0.658)

0.685

(0.628–0.738)

0.469

(0.421–0.518)

0.800

(0.760–0.835)

0.640

(0.608–0.672)

TyG

0.627

(0.587–0.666)

0.828

(0.795–0.858)

0.377

(0.321–0.436)

0.519

(0.449–0.588)

0.730

(0.694–0.763)

0.679

(0.647–0.710)

TyG-WHtR

0.705

(0.668–0.743)

0.676

(0.637–0.714)

0.640

(0.582–0.696)

0.493

(0.442–0.545)

0.792

(0.754–0.827)

0.664

(0.632–0.696)

METS-IR

0.685

(0.648–0.722)

0.404

(0.364–0.445)

0.862

(0.816–0.899)

0.416

(0.376–0.456)

0.856

(0.809–0.895)

0.555

(0.521–0.588)

Hepatic fibrosis

HOMA-IR

0.682

(0.635–0.729)

0.603

(0.520–0.681)

0.708

(0.673–0.740)

0.895

(0.867–0.919)

0.300

(0.249–0.355)

0.689

(0.658–0.720)

TyG

0.542

(0.489–0.594)

0.576

(0.493–0.656)

0.506

(0.469–0.543)

0.852

(0.814–0.884)

0.196

(0.160–0.235)

0.518

(0.485–0.552)

TyG-WHtR

0.703

(0.655–0.751)

0.629

(0.547–0.706)

0.712

(0.677–0.744)

0.902

(0.875–0.925)

0.313

(0.261–0.368)

0.697

(0.666–0.728)

METS-IR

0.682

(0.632–0.731)

0.589

(0.507–0.669)

0.709

(0.674–0.742)

0.892

(0.864–0.916)

0.297

(0.246–0.352)

0.688

(0.657–0.719)

  1. METS-IR metabolic score for insulin resistance, TyG triglyceride/glucose, HOMA-IR homeostasis model assessment of IR, TyG-WHtR triglyceride glucose-waist-to-height ratio, AUC the area under of curve, CI confidence interval, PPV positive predictive value, NPV negative predictive value