Table 2 Comparison of 3D HRAM parameters between the HFI and MRW subgroups at different ages
Variable | Individuals aged ≥ 50 years (49 cases) vs. < 50 years (n = 11) in the HFI subgroup | P | Individuals aged ≥ 50 years (47 cases) vs. < 50 years (n = 21) in the MRW subgroup | P | Individuals aged ≥50 years HFI group (49 cases) vs. ≥50 years MRW subgroup (47 cases) | P | Individuals aged < 50 years HFI subgroup (11 cases) vs. < 50 years MRW subgroup (21 cases) | P |
|---|---|---|---|---|---|---|---|---|
OR 95%(CI | OR 95%(CI) | OR 95%(CI) | OR 95%(CI) | |||||
Rest | ||||||||
Maximum resting pressure (mmHg) | 5.90(-19.10~4.52) | 0.22 | 7.31(-10.49~18.70) | 0.57 | 4.93(-41.82~-22.24) | 0.00 | 8.31(-37.37~-3.46) | 0.03 |
Mean resting pressure (mmHg) | 5.17(-16.44~4.27) | 0.24 | 6.14(-6.70~17.82) | 0.37 | 4.10(-36.69~20.37) | 0.00 | 7.95(-32.73~0.17) | 0.03 |
HPZ length (cm) | 0.22(-0.47~0.40) | 0.87 | 0.18(-0.54~0.17) | 0.30 | 0.14(-0.47~0.08) | 0.16 | 0.25(-0.81~0.22) | 0.26 |
Squeeze | ||||||||
Maximum squeezing pressure (mmHg) | 17.51(-77.64~-7.52) | 0.02 | 13.18(-30.19~22.45) | 0.77 | 9.49(-45.64~--7.94) | 0.01 | 25.55(-40.71~63.97) | 0.61 |
Duration of sustained squeeze (s) | 1.88(-4.84~2.69) | 0.57 | 1.41(-3.27~2.38) | 0.76 | 1.15(-4.43~0.12) | 0.06 | 2.03(-5.89~0.15) | 0.38 |
Simulated defecation | ||||||||
Residual anal pressure (mmHg) | 9.29(-22.73~14.47) | 0.66 | 8.29(-7.81~25.28) | 0.30 | 6.03(-36.69~-12.73) | 0.00 | 11.60(-36.18~11.13) | 0.29 |
Anal relaxation rate (%) | 5.79(-19.07~4.10) | 0.20 | 7.21(-30.53~-1.72) | 0.03 | 4.52(-7.71~10.44) | 0.77 | 9.59(-27.29~-11.84) | 0.43 |
Intrarectal pressure (mmHg) | 8.80(-21.47~13.76) | 0.39 | 5.90(-7.02~16.54) | 0.42 | 5.13(-23.24~-2.24) | 0.02 | 7.27(-18.61~11.06) | 0.61 |
Rectoanal pressure differential (mmHg) | 16.14(-27.42~37.20) | 0.76 | 9.78(-20.89~81.17) | 0.89 | 9.09(1.77~37.86) | 0.03 | 14.09(-14.48~43.01) | 0.32 |
Graded balloon distension | ||||||||
Anorectal inhibitory reflex | 3.13(-3.18~9.38) | 0.33 | 2.42(-6.08~3.1807) | 0.61 | 1.97(-9.79~-1.96) | 0.04 | 3.09(-14.64~2.30) | 0.00 |
First sensation (cc) | 5.44(-7.56~14.20) | 0.54 | 5.20(-8.85~11.89) | 0.77 | 3.76(-6.30~8.63) | 0.76 | 6.64(-13.09~14.00) | 0.95 |
Urge to defecate (cc) | 5.44(-7.56~14.20) | 0.25 | 9.71(-17.34~21.45) | 0.83 | 7.39(-3.63~25.72) | 0.14 | 12.24(-23.20~26.93) | 0.78 |
Maximum tolerated volume (cc) | 10.75(-17.75~29.45) | 0.62 | 9.77(-17.08~21.92) | 0.81 | 7.18(-9.30~19.33) | 0.49 | 14.72(-25.48~34.57) | 0.76 |
Defecation index | 0.21(-0.71~0.12) | 0.16 | 0.10(-0.17~0.25) | 0.96 | 0.11(-0.34~0.11) | 0.28 | 0.14(-0.06~0.51) | 0.12 |