Fig. 3

ARID1A deficiency correlated with increased tumour mutation burden and higher mutation rate in DDR pathways. a ARID1A-deficient HBV-HCC had a significantly higher tumour mutational burden. b The difference in the mutation rate of DNA damage repair pathways between the two groups. c, d ARID1A deficiency significantly coexisted with mutations in base-excision repair (BER) genes and mismatch repair (MMR) genes. (* P < 0.05, ** P < 0.01, *** P < 0.001)