Table 2 Results of target enrichment sequencing
| Â | Â | Â | Â | Recurrence | Non-recurrence | Â | ||
|---|---|---|---|---|---|---|---|---|
Gene symbol | Exonic function | Nucleotide change | Aa change | RefSeq (n) | AltSeq (n) | RefSeq (n) | AltSeq (n) | p-value |
PINK1 | non-synonymous SNV | NM_032409:c.1018G > A | p.A340T | 21 (80.8) | 5 (19.2) | 27 (47.4) | 30 (52.6) | 0.0045 |
PINK1 | non-synonymous SNV | NM_032409:c.1562A > C | p.N521T | 19 (70.4) | 8 (29.6) | 22 (38.6) | 35 (61.4) | 0.0098 |
KRAS | synonymous SNV | NM_001369787:c.519 T > C | p.D173D | 16 (59.3) | 11 (40.7) | 47 (82.5) | 10 (17.5) | 0.0311 |
DEPTOR | synonymous SNV | NM_022783:c.135C > T | p.H45H | 24 (88.9) | 3 (11.1) | 57 (100) | 0 (0) | 0.0307 |
OPTN | synonymous SNV | NM_021980:c.102G > A | p.T34T | 14 (51.9) | 13 (48.1) | 44 (77.2) | 13 (22.8) | 0.0245 |