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Table 5 Risk factors for poor sedation

From: The efficacy of non-anesthesiologist-administered propofol sedation with a target-controlled infusion system during double-balloon endoscopic retrograde cholangiopancreatography

 

n

Number of patients with poor sedation

Univariate analysis

Multivariate analysis

OR (95% CI)

P value

OR (95% CI)

P value

Age < 70 years old

71

10

4.48

(1.18–16.98)

0.027

10.26

(1.57–66.98)

0.015

Sex, male

94

7

0.75

(0.24–2.35)

0.623

   

BMI ≥ 25 kg/m2

13

6

16.65

(4.41–62.90)

< 0.0001

11.96

(1.67–85.69)

0.014

Current or ex-smoker

76

6

0.89

(0.29–2.79)

0.847

   

Alcohol abuse

36

5

2.26

(0.69–7.39)

0.178

   

Regular narcotic/sedative use

33

1

0.29

(0.04–2.31)

0.242

   

Heart disease

18

1

0.62

(0.08–5.05)

0.653

   

Lung disease

14

1

0.83

(0.10–6.93)

0.866

   

Renal or liver disease

21

2

1.19

(0.24–5.77)

0.832

   

ASA class 3

21

3

2.08

(0.52–8.29)

0.298

   

Roux-en-Y anastomosis

69

11

8.06

(1.72–37.72)

0.008

3.80

(0.65–22.39)

0.140

Procedure time ≥ 60 min

79

12

13.61

(1.72–107.47)

0.013

4.72

(0.49–45.08)

0.178

Cholangitis

42

2

0.46

(0.10–2.19)

0.331

   

Propofol sedation

79

1

0.07

(0.01–0.55)

0.011

0.06

(0.01–0.58)

0.015

  1. OR odds ratio, CI confidence interval, BMI body mass index, ASA American Society of Anesthesiologists