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Table 4 Infusion drug doses and sedation-related adverse events

From: The efficacy of non-anesthesiologist-administered propofol sedation with a target-controlled infusion system during double-balloon endoscopic retrograde cholangiopancreatography

 

Diazepam sedation (n = 77)

Propofol sedation (n = 79)

P value

Procedure time, mean ± SD, minutes

68.7 ± 40.1

59.0 ± 26.3

0.159

Total infusion dose of diazepam, mean ± SD, mg

9.7 ± 4.6

  

Total infusion dose of pethidine, mean ± SD, mg

93.6 ± 33.2

  

Total infusion dose of propofol, mean ± SD, mg

 

317.0 ± 145.9

 

Total infusion dose of pentazocine, mean ± SD, mg

 

15.0 ± 0

 

Procedure-related success, n (%)

63 (82)

65 (82)

0.940

Post-ERCP pancreatitis, n (%)

0 (0)

0 (0)

-

Poor sedation, n (%)

12 (16)

1 (1)

0.001

Required other sedative agents/discontinued the procedure

12/0

0/1

 

Vigorous body movement (4 or 5), n (%)

40 (52)

28 (35)

0.038

Bradycardia (< 50/minute), n (%)

7 (9)

4 (5)

0.326

Hypotension (< 90/50 mmHg or down 20%), n (%)

13 (17)

21 (27)

0.142

Hypoxemia (< 85%), n (%)

7 (9)

1 (1)

0.027

  1. SD standard deviation, ERCP endoscopic retrograde cholangiopancreatography