Table 1 Correlation between HHIP expression and clinical characteristics of CRC
Characteristics | Low expression of HHIP | High expression of HHIP | P value |
|---|---|---|---|
n | 322 | 322 | |
Pathologic T stage, n (%) | 0.234 | ||
T1 | 12 (1.9%) | 8 (1.2%) | |
T2 | 62 (9.7%) | 49 (7.6%) | |
T3 | 217 (33.9%) | 219 (34.2%) | |
T4 | 31 (4.8%) | 43 (6.7%) | |
Pathologic N stage, n (%) | 0.008 | ||
N0 | 203 (31.7%) | 165 (25.8%) | |
N1 | 62 (9.7%) | 91 (14.2%) | |
N2 | 57 (8.9%) | 62 (9.7%) | |
Pathologic M stage, n (%) | 0.378 | ||
M0 | 243 (43.1%) | 232 (41.1%) | |
M1 | 41 (7.3%) | 48 (8.5%) | |
Pathologic stage, n (%) | 0.082 | ||
Stage I | 63 (10.1%) | 48 (7.7%) | |
Stage II | 128 (20.5%) | 110 (17.7%) | |
Stage III | 81 (13%) | 103 (16.5%) | |
Stage IV | 41 (6.6%) | 49 (7.9%) | |
Perineural invasion, n (%) | 0.023 | ||
No | 91 (38.7%) | 84 (35.7%) | |
Yes | 21 (8.9%) | 39 (16.6%) | |
Lymphatic invasion, n (%) | 0.090 | ||
No | 182 (31.3%) | 168 (28.9%) | |
Yes | 104 (17.9%) | 128 (22%) |