Table 3 Exposure to angiotensin receptor blockers (ARB) and severity of acute pancreatitis, estimated by odds ratios (OR) with 95% confidence intervals (CI)
Exposure | Controls | Mild acute pancreatitis | Moderate acute pancreatitis | Severe acute pancreatitis |
|---|---|---|---|---|
N (%) | N (%) | N (%) | N (%) | |
Total, n (%) | 61,637 (100) | 2,783 (100) | 1,542 (100) | 1,814 (100) |
ARB | 56,542 (92) | 2,514 (90) | 1,403 (91) | 1,632 (90) |
Never use | ||||
Current use | 4,715 (8) | 249 (9) | 131 (8.5) | 168 (9) |
Model 1 OR (95 % CI) | 1 (Reference) | 1 · 25 (1 · 10–1 · 44) | 1 · 08 (0 · 90–1 · 30) | 1 · 18 (1 · 00–1 · 39) |
Model 2 (OR (95 % CI) | 0 · 86 (0 · 75–0 · 99) | 0 · 73 (0 · 61–0 · 88) | 0 · 76 (0 · 64–0 · 89) | |
Model 3 OR (95 % CI) | 0 · 81 (0 · 70–0 · 94) | 0 · 71 (0 · 58–0 · 87) | 0 · 71 (0 · 59–0 · 85) | |
Past use | 380 (1) | 20 (0.5) | 8 (0.5) | 14 (1) |
Model 1 OR (95 % CI) | 1 (Reference) | 1 · 24 (0 · 79–1 · 95) | 0 · 82 (0 · 41–1 · 66) | 1 · 23 (0 · 72–2 · 10) |
Model 2 OR (95 % CI) | 0 · 85 (0 · 54–1 · 33) | 0.56 (0.28–1.13) | 0 · 79 (0 · 49–1 · 35) | |
Model 3 OR (95 % CI) | 0 · 75 (0 · 46–1 · 22) | 0.53 (0 · 26–1 · 08) | 0 · 75 (0 · 42–1 · 29) |