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Table 1 Demographic characteristics and clinical parameters of the study subjects

From: A preliminary investigation on single nucleotide polymorphism rs2287622 of bile salt export pump gene in patients with chronic hepatitis C virus infection in Hunan, China

Parmeter

CHC

CHB

Healthy

P value

n

165

99

99

Gender male (n, %)

88 (53.3)

50 (50.5)

50 (50.5)

NS

Age, years (mean ± SD, range)

43.3 ± 11.9 (18–70)

43.5 ± 12.3 (22–67)

40.3 ± 12.2 (18–68)

NS

BMI (mean ± SD, range)

23.2 ± 3.9 (16.5–34.6)

22.6 ± 3.5 (18.4–33.9)

23.8 ± 3.4 (17.1–32.3)

NS

ALT, IU/L (median ± SD, IQR)

82.0 ± 62.0 (70.2)

94.1 ± 65.1 (83.6)

normal

NSb

AST, IU/L (median ± SD, IQR)

65.6 ± 40.4 (50.1)

77.4 ± 42.0 (68.0)

normal

NSb

HCV RNA level, log IU/mL (median ± SD, IQR)

6.08 ± 1.35 (1.51)

HBV DNA level, log IU/mL (median, IQR)

5.97 ± 1.21 (1.43)

  1. BMI body mass index, SD standard deviation, IQR interquartile range, NS non-significant, P > 0.05
  2. aThe clinical data of the patients treated with anti-HCV or anti-HBV therapy were collected at the start point of the treatment, while data of the other patients were collected on the day when the genomic DNA were collected
  3. bComparisons of serum aminotransferase levels were carried out only between patients with chronic HCV infection and those with chronic HBV infection