Fig. 2

Presence of diseases considered to be extra-intestinal manifestations in prevalent children with inflammatory bowel disease (n = 1432), ulcerative colitis (n = 585), Crohn’s disease (n = 548), IBD unclassified (n = 299) and in matched general population controls (n = 8583; matched by age, sex, and county of residence at time of identification). * p < 0.01 for comparison between children with IBD, UC; CD or IBD-U and matched controls; Patients required to have at least 2 listings of the selected diagnoses to be defined as a case; Rheumatic diseases defined as rheumatoid arthritis, psoriatic and enteropathic arthropathies, juvenile arthritis, unspecified arthritis, pain in joints, Sjögrens syndrome, Behcet’s disease, ankylosing spondylitis; Dermatologic diseases defined as pyoderma gangraenosum, erythema nodosum, psoriasis, febrile neutrophilic dermatosis, aphthous stomatitis; Hepatobiliary diseases defined as primary sclerosing cholangitis, pericholangitis, cholelithiasis, chronic active hepatitis, nonalcoholic fatty liver disease; Pancreatic diseases defined as acute or chronic pancreatitis; Codes used in this analysis are available in the SDC, Additional file 5: Table S5; patients IBD-U defined as patients with both a UC and a CD diagnosis during follow up