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Table 3 Third trimester fetal and maternal complications (27–42 wks)

From: Does lower gastrointestinal endoscopy during pregnancy pose a risk for mother and child? – a systematic review

Indication

N

Maternal adverse events

Pregnancy outcome

Premature birth

Fetal adverse events

Temporal relation with endoscopy?

Etiological relation with endoscopy?

Sigmoidoscopy

IBD & colitis other [11,64,65]

3

None (n = 2), subtotal colectomy with ileostomy after delivery (n = 1)

Live birth (n = 3)

No (n = 1), Yes (n = 2)

Premature births (28 and 34 wks), low birth weight (1850 and 1054 g)

No (n = 2), yes (n = 1)

Likely, after sigmoidoscopy colonic perforation was suspected, this led to an emergency caesarean section.

Malignancy [66-70]

5

Not reported (n = 3), death 12 months after hemicolectomy (n = 1), 1,5 years after delivery discovery of pulmonary metastases (n = 1)

Live birth (n = 5)

Yes (n = 4), No (n = 1)

Premature births at 34, 34, 31 and 33 wks, all deliveries were elective, low birth weight reported (n = 2)

No

Unlikely

Volvulus and incarcerated uterus [49,71-73]

5 (in 4 pts)

None

Live birth (n = 4)

None

None

Yes (n = 1)

Unlikely

Non-malignant colonic obstruction [74,75]

2

None

Live birth (n = 1), not reported (n = 1)

Yes (n = 1)

Elective caesarean section (n = 1), Not reported (n = 1)

Yes (n = 1)

Unlikely

Gastrointestinal bleeding

0

-

-

-

-

-

-

Colonoscopy

IBD & colitis other [52,76]

2

Intensive care unit admittance postpartum (n = 1), none (n = 1)

Live birth (n = 1), not reported (n = 1)

Yes (n = 1), not reported (n = 1)

Premature birth (32 wks) with low birth weight 2175 grams

No

Unlikely

Malignancy [77-84]

8

None (n = 4), maternal death after delivery due to disease progression (n = 4)

Live birth (n = 8)

Yes (n = 8)

Premature births by elective caesarean section (n = 4), spontaneous premature birth (n = 4)

Yes (n = 1), no (n = 7)

Unlikely

Volvulus and incarcerated uterus

0

-

-

-

-

-

-

Non-malignant colonic obstruction [85,86]

3 (in 2 pts)

None

Live birth (n = 1), live twin birth (n = 1)

Yes (n = 1)

Spontaneous premature birth of twins at wk 34

Yes

Possible, however nifedipine was also stopped around time of LGE

Gastrointestinal bleeding [87]

1

None

Elective termination at 34 wks

Yes

Not reported

No

Unlikely

Total

29