Table 7 Comparison of the clinical characteristics of chronic hepatitis C patients with (A2–3) or without (A0–1) severe hepatic inflammation
| Â | Â | A0-A1 | Â | A2-A3 | Â | Â | Â |
|---|---|---|---|---|---|---|---|
|  |  | n = 32 |  | n = 45 |  |  |  |
Factor | Mean or number | Maximum | Minimum | Mean or number | Maximum | Minimum | P value* |
Age (years) | 51.9 | 70 | 20 | 59.1 | 76 | 24 | 0.039 |
Sex (male/female) | 14/18 | Â | Â | 17/28 | Â | Â | 0.598 |
Body mass index (kg/m2) | 23.1 | 30.1 | 16.4 | 23.7 | 32.2 | 17.8 | 0.694 |
Platelets (×104/μl) | 21.3 | 41.9 | 11.1 | 15.8 | 39.7 | 5.4 | <0.001 |
Total cholesterol (mg/dl) | 180.9 | 295 | 101 | 163.4 | 251 | 84 | 0.122 |
Albumin (g/dl) | 4.4 | 5.1 | 3.3 | 4.2 | 4.9 | 2.9 | 0.003 |
ALT (IU/l) | 42.2 | 165 | 13 | 80.3 | 244 | 14 | 0.003 |
γ-GTP (IU/l) | 32.3 | 114 | 12 | 62.8 | 468 | 12 | 0.006 |
Diabetes (absent/present) | 6/26 | Â | Â | 11/34 | Â | Â | 0.553 |
Fasting plasma glucose (mg/dl) | 97.8 | 196 | 75 | 96.5 | 176 | 72 | 0.983 |
Hemoglobin A1c (%) | 5.4 (n = 31) | 7.6 | 4.6 | 5.4 (n = 44) | 7.1 | 4.7 | 0.643 |
Leptin (ng/ml) | 7.2 | 21.8 | 1 | 7.8 | 20.7 | 1.1 | 0.247 |
Adiponectin (ng/ml) | 8.9 | 27.3 | 1.1 | 9 | 26.7 | 1.7 | 0.463 |
Resistin (ng/ml) | 8.6 | 27.6 | 2.5 | 8.5 | 19.7 | 3 | 0.687 |
AIM (μg/ml) | 1.17 | 4.56 | 0.41 | 1.54 | 6.44 | 0.76 | 0.001 |
Hyaluronic acid (ng/ml) | 58.8 | 10.0 | 292.7 | 123.4 (n = 43) | 12.1 | 636.0 | 0.001 |