Characteristics | TF group (n = 39) | PPI group (n = 21) | p values |
---|---|---|---|
Male, n (%) | 19 (49) | 8 (38) | 0.587 |
Age, years | 54.5 (10.4) | 50.4 (9.8) | 0.151 |
Body mass index, kg/m2 | 28.3 (3.9) | 29.1 (2.8) | 0.422 |
GERD symptom duration, years | 12.5 (11.3) | 9.4 (5.7) | 0.224 |
PPI therapy duration, years | 9.3 (7.2) | 8.1 (5.1) | 0.686 |
Quality of life scores off PPIs | |||
Reflux Disease Questionnaire (RDQ) score | 3.7 (1.1) | 4.1 (0.7) | 0.122 |
Regurgitation (RDQ) score off PPIs | 3.5 (1.2) | 4.1 (0.9) | 0.067 |
GERD-HRQL score | 32.5 (9.6) | 33.7 (8.5) | 0.625 |
Heartburn score (GERD-HRQL) | 22.2 (6.3) | 23.2 (4.4) | 0.519 |
Reflux Symptom Index (RSI) score | 25.2 (9.3) | 28.6 (7.4) | 0.150 |
Total % time pH <4 | 10.2 (3.5) | 10.6 (3.5) | 0.665 |
Patients on single dose of PPI at entry, n (%) | 27 (69) | 16 (76) | 0.765 |